Hypothyroidism is a relatively common medical condition and around 3% to 5% of the population have it. It is marked by a lack of thyroid hormones which could directly or indirectly include the thyroid gland. Here are some of the key factors behind hypothyroidism.
One of the key cause of hypothyroidism is the hereditary condition referred to as Hashimoto’s thyroiditis. It is an autoimmune condition wherein the immune system assaults the thyroid gland. Due to this, the thyroid gland becomes enlarged and has a decreased capability to produce thyroid hormones. Women are 5 to 10 times more prone to have Hashimoto’s thyroiditis than males, therefore making them more susceptible to hypothyroiditis.
Iodine deficiency may also result in hypothyroidism. Iodine is an crucial constituent in the thyroid hormones thyroxine and triiodothyronine and therefore lack of it in the body might cause difficulties in the creation of these vital hormones.
Another root cause of an under active thyroid is a condition of the thyroid glands referred to as lymphocytic thyroiditis. A white blood cell called lymphocyte leads to the inflammation of the thyroid glands. This is very frequent after giving birth, affecting 8% of women after giving birth. The illness will be started by a hyperthyroid period in which the thyroid gland secretes abnormal amounts of thyroid hormones. It is accompanied by the hypothyroid period which can last as much as 6 months.
Ironically, a few medical treatments could also trigger an under active thyroid. Iodine-131, a radioisotope of iodine that is used to help remedy a thyroid condition called Graves’ disease, can severely affect the thyroid gland. Other drugs which are utilized to address hyperthyroidism could also trigger an under active thyroid too such as methimazole and propylthiouracil. The psychiatric medication lithium and medicines that contain considerable amounts of iodine like amiodarone and potassium iodide can also alter the thyroid function, resulting in the hypothyroidism.
Hypothyroidism that indirectly involves the thyroid glands are classified as secondary and tertiary hypothyroidism. This happens when there is problem in the pituitary glands and the hypothalamus, respectively, and they can't signal the thyroid glands to generate sufficient hormones. This occurs when the pituitary glands are unable to release thyroid stimulating hormone (TSH), usually because of a tumor in the pituitary gland or the hypothalamus.